CD97 is associated with mitogenic pathway activation, metabolic reprogramming, and immune microenvironment changes in glioblastoma

Glioblastoma (GBM) is the most common primary brain tumor with a median survival under two years. Using in silico and in vitro techniques, we demonstrate heterogeneous expression of CD97, a leukocyte adhesion marker, in human GBM. Beyond its previous demonstrated role in tumor invasion, we show that...

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Detalles Bibliográficos
Autores principales: Safaee, Michael M., Wang, Elaina J., Jain, Saket, Chen, Jia-Shu, Gill, Sabraj, Zheng, Allison C., Garcia, Joseph H., Beniwal, Angad S., Tran, Y., Nguyen, Alan T., Trieu, Melissa, Leung, Kevin, Wells, Jim, Maclean, James M., Wycoff, Keith, Aghi, Manish K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795421/
https://www.ncbi.nlm.nih.gov/pubmed/35087132
http://dx.doi.org/10.1038/s41598-022-05259-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795421/
https://www.ncbi.nlm.nih.gov/pubmed/35087132
http://dx.doi.org/10.1038/s41598-022-05259-y

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