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A molecular atlas of innate immunity to adjuvanted and live attenuated vaccines, in mice

Adjuvants hold great potential in enhancing vaccine efficacy, making the understanding and improving of adjuvants critical goals in vaccinology. The TLR7/8 agonist, 3M-052, induces long-lived humoral immunity in non-human primates and is currently being evaluated in human clinical trials. However, t...

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Detalles Bibliográficos
Autores principales: Lee, Audrey, Scott, Madeleine K. D., Wimmers, Florian, Arunachalam, Prabhu S., Luo, Wei, Fox, Christopher B., Tomai, Mark, Khatri, Purvesh, Pulendran, Bali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795432/
https://www.ncbi.nlm.nih.gov/pubmed/35087093
http://dx.doi.org/10.1038/s41467-022-28197-9