Cargando…

Ultrafast end-to-end protein structure prediction enables high-throughput exploration of uncharacterized proteins

Deep learning-based prediction of protein structure usually begins by constructing a multiple sequence alignment (MSA) containing homologs of the target protein. The most successful approaches combine large feature sets derived from MSAs, and considerable computational effort is spent deriving these...

Descripción completa

Detalles Bibliográficos
Autores principales: Kandathil, Shaun M., Greener, Joe G., Lau, Andy M., Jones, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795500/
https://www.ncbi.nlm.nih.gov/pubmed/35074909
http://dx.doi.org/10.1073/pnas.2113348119