Pathogenic TNF-α drives peripheral nerve inflammation in an Aire-deficient model of autoimmunity

Immune cells infiltrate the peripheral nervous system (PNS) after injury and with autoimmunity, but their net effect is divergent. After injury, immune cells are reparative, while in inflammatory neuropathies (e.g., Guillain Barré Syndrome and chronic inflammatory demyelinating polyneuropathy), immu...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yan, Guo, Lily, Yin, Xihui, McCarthy, Ethan C., Cheng, Mandy I., Hoang, Aline T., Chen, Ho-Chung, Patel, Anushi Y., Allard Trout, Denise, Xu, Erin, Yakobian, Natalie, Hugo, Willy, Howard, James F., Sheu, Katherine M., Hoffmann, Alexander, Lechner, Melissa G., Su, Maureen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795502/
https://www.ncbi.nlm.nih.gov/pubmed/35058362
http://dx.doi.org/10.1073/pnas.2114406119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795502/
https://www.ncbi.nlm.nih.gov/pubmed/35058362
http://dx.doi.org/10.1073/pnas.2114406119

Ejemplares similares