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Pathogenic TNF-α drives peripheral nerve inflammation in an Aire-deficient model of autoimmunity
Immune cells infiltrate the peripheral nervous system (PNS) after injury and with autoimmunity, but their net effect is divergent. After injury, immune cells are reparative, while in inflammatory neuropathies (e.g., Guillain Barré Syndrome and chronic inflammatory demyelinating polyneuropathy), immu...
Autores principales: | Wang, Yan, Guo, Lily, Yin, Xihui, McCarthy, Ethan C., Cheng, Mandy I., Hoang, Aline T., Chen, Ho-Chung, Patel, Anushi Y., Allard Trout, Denise, Xu, Erin, Yakobian, Natalie, Hugo, Willy, Howard, James F., Sheu, Katherine M., Hoffmann, Alexander, Lechner, Melissa G., Su, Maureen A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795502/ https://www.ncbi.nlm.nih.gov/pubmed/35058362 http://dx.doi.org/10.1073/pnas.2114406119 |
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