Structure and function of an effector domain in antiviral factors and tumor suppressors SAMD9 and SAMD9L

SAMD9 and SAMD9L (SAMD9/9L) are antiviral factors and tumor suppressors, playing a critical role in innate immune defense against poxviruses and the development of myeloid tumors. SAMD9/9L mutations with a gain-of-function (GoF) in inhibiting cell growth cause multisystem developmental disorders inc...

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Detalles Bibliográficos
Autores principales: Peng, Shuxia, Meng, Xiangzhi, Zhang, Fushun, Pathak, Prabhat Kumar, Chaturvedi, Juhi, Coronado, Jaime, Morales, Marisol, Mao, Yuanhui, Qian, Shu-Bing, Deng, Junpeng, Xiang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795524/
https://www.ncbi.nlm.nih.gov/pubmed/35046037
http://dx.doi.org/10.1073/pnas.2116550119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795524/
https://www.ncbi.nlm.nih.gov/pubmed/35046037
http://dx.doi.org/10.1073/pnas.2116550119

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