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Phagocytosis and self-destruction break down dendrites of Drosophila sensory neurons at distinct steps of Wallerian degeneration

After injury, severed dendrites and axons expose the “eat-me” signal phosphatidylserine (PS) on their surface while they break down. The degeneration of injured axons is controlled by a conserved Wallerian degeneration (WD) pathway, which is thought to activate neurite self-destruction through Sarm-...

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Detalles Bibliográficos
Autores principales: Ji, Hui, Sapar, Maria L., Sarkar, Ankita, Wang, Bei, Han, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795528/
https://www.ncbi.nlm.nih.gov/pubmed/35058357
http://dx.doi.org/10.1073/pnas.2111818119