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V-CARMA: A tool for the detection and modification of antigen-specific T cells

T cells promote our body’s ability to battle cancers and infectious diseases but can act pathologically in autoimmunity. The recognition of peptides presented by major histocompatibility complex (pMHC) molecules by T cell receptors (TCRs) enables T cell–mediated responses. To modify disease-relevant...

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Detalles Bibliográficos
Autores principales: Guo, Xi-zhi J., Elledge, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795542/
https://www.ncbi.nlm.nih.gov/pubmed/35042811
http://dx.doi.org/10.1073/pnas.2116277119