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Rad54 and Rdh54 prevent Srs2-mediated disruption of Rad51 presynaptic filaments

Srs2 is a superfamily 1 (SF1) helicase that participates in several pathways necessary for the repair of damaged DNA. Srs2 regulates formation of early homologous recombination (HR) intermediates by actively removing the recombinase Rad51 from single-stranded DNA (ssDNA). It is not known whether and...

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Detalles Bibliográficos
Autores principales: Meir, Aviv, Crickard, J. Brooks, Kwon, Youngho, Sung, Patrick, Greene, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795549/
https://www.ncbi.nlm.nih.gov/pubmed/35042797
http://dx.doi.org/10.1073/pnas.2113871119