Cargando…
DNA-induced spatial entrapment of general transcription machinery can stabilize gene expression in a nondividing cell
An important characteristic of cell differentiation is its stability. Only rarely do cells or their stem cell progenitors change their differentiation pathway. If they do, it is often accompanied by a malfunction such as cancer. A mechanistic understanding of the stability of differentiated states w...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795562/ https://www.ncbi.nlm.nih.gov/pubmed/35074915 http://dx.doi.org/10.1073/pnas.2116091119 |