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The Contribution of Liver Sinusoidal Endothelial Cells to Clearance of Therapeutic Antibody

Many chronic inflammatory diseases are treated by administration of “biological” therapies in terms of fully human and humanized monoclonal antibodies or Fc fusion proteins. These tools have widespread efficacy and are favored because they generally exhibit high specificity for target with a low tox...

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Detalles Bibliográficos
Autores principales: James, Bethany H., Papakyriacou, Pantelitsa, Gardener, Matthew J., Gliddon, Louise, Weston, Christopher J., Lalor, Patricia F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795706/
https://www.ncbi.nlm.nih.gov/pubmed/35095549
http://dx.doi.org/10.3389/fphys.2021.753833