TRK-fused gene (TFG) regulates ULK1 stability via TRAF3-mediated ubiquitination and protects macrophages from LPS-induced pyroptosis

TRK-fused gene (TFG) is known to be involved in protein secretion and plays essential roles in an antiviral innate immune response. However, its function in LPS-induced inflammation and pyroptotic cell death is still unknown. Here, we reported that TFG promotes the stabilization of Unc-51 like autop...

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Detalles Bibliográficos
Autores principales: Shi, Jian-Hong, Ling, Chen, Wang, Ting-Ting, Zhang, Li-Nuo, Liu, Wen-Wen, Qin, Yan, Tan, Ying-Hui, Cui, Nai-Peng, Ni, Zhi-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795729/
https://www.ncbi.nlm.nih.gov/pubmed/35091545
http://dx.doi.org/10.1038/s41419-022-04539-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795729/
https://www.ncbi.nlm.nih.gov/pubmed/35091545
http://dx.doi.org/10.1038/s41419-022-04539-9

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