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Preclinical Evaluation of Dimethyl Itaconate Against Hepatocellular Carcinoma via Activation of the e/iNOS-Mediated NF-κB–Dependent Apoptotic Pathway

Hepatocellular carcinoma (HCC) is one of the most common tumors affecting a large population worldwide, with the fifth and seventh greatest mortality rates among men and women, respectively, and the third prime cause of mortality among cancer victims. Dimethyl itaconate (DI) has been reported to be...

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Detalles Bibliográficos
Autores principales: Gautam, Anurag Kumar, Kumar, Pranesh, Raj, Ritu, Kumar, Dinesh, Bhattacharya, Bolay, Rajinikanth, P.S., Chidambaram, Kumarappan, Mahata, Tarun, Maity, Biswanath, Saha, Sudipta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795766/
https://www.ncbi.nlm.nih.gov/pubmed/35095533
http://dx.doi.org/10.3389/fphar.2021.823285