STING Signaling Drives Production of Innate Cytokines, Generation of CD8(+) T Cells and Enhanced Protection Against Trypanosoma cruzi Infection

A variety of signaling pathways are involved in the induction of innate cytokines and CD8(+) T cells, which are major players in protection against acute Trypanosoma cruzi infection. Previous data have demonstrated that a TBK-1/IRF3-dependent signaling pathway promotes IFN-β production in response t...

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Detalles Bibliográficos
Autores principales: Vieira, Raquel de Souza, Nascimento, Marilda Savoia, Noronha, Isaú Henrique, Vasconcelos, José Ronnie Carvalho, Benvenuti, Luiz Alberto, Barber, Glen N., Câmara, Niels Olsen Saraiva, Kalil, Jorge, Cunha-Neto, Edecio, Almeida, Rafael Ribeiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795786/
https://www.ncbi.nlm.nih.gov/pubmed/35095849
http://dx.doi.org/10.3389/fimmu.2021.775346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795786/
https://www.ncbi.nlm.nih.gov/pubmed/35095849
http://dx.doi.org/10.3389/fimmu.2021.775346

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