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Decrease of IL-1β and TNF in the Spinal Cord Mediates Analgesia Produced by Ankle Joint Mobilization in Complete Freund Adjuvant-Induced Inflammation Mice Model

OBJECTIVE: This study aims to investigate the effects of ankle joint mobilization (AJM) on mechanical hyperalgesia and peripheral and central inflammatory biomarkers after intraplantar (i.pl.) Complete Freund’s Adjuvant (CFA)-induced inflammation. METHODS: Male Swiss mice were randomly assigned to 3...

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Detalles Bibliográficos
Autores principales: Omura, Carlos Minoru, Lüdtke, Daniela Dero, Horewicz, Verônica Vargas, Fernandes, Paula Franson, Galassi, Taynah de Oliveira, Salgado, Afonso Shiguemi Inoue, Palandi, Juliete, Baldança, Heloiza dos Santos, Bittencourt, Edsel B., Mack, Josiel Mileno, Seim, Lynsey A., Martins, Daniel Fernandes, Bobinski, Franciane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795789/
https://www.ncbi.nlm.nih.gov/pubmed/35095573
http://dx.doi.org/10.3389/fphys.2021.816624