Cargando…

MiR-25 enhances autophagy and promotes sorafenib resistance of hepatocellular carcinoma via targeting FBXW7

Sorafenib resistance is a major challenge in the treatment of patients with advanced hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) are a large family of non-coding RNA molecules, which is an important mechanism of drug resistance. We previously found that knockdown of miR-25 increased the sensi...

Descripción completa

Detalles Bibliográficos
Autores principales: Feng, Xiaoning, Zou, Bei, Nan, Tianhao, Zheng, Xiaoxiao, Zheng, Li, Lan, Jiahua, Chen, Wei, Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795798/
https://www.ncbi.nlm.nih.gov/pubmed/35165511
http://dx.doi.org/10.7150/ijms.67352