Upregulation of C/EBP Homologous Protein induced by ER Stress Mediates Epithelial to Myofibroblast Transformation in ADTKD-UMOD

Autosomal dominant tubulointerstitial kidney disease due to UMOD mutations (ADTKD-UMOD) results in chronic interstitial nephritis, which gradually develops into end-stage renal disease. It is believed that the accumulation of mutant uromodulin causes the endoplasmic reticulum (ER) stress, then leads...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Qiu, Yagui, Fan, Jinjin, Liu, Yuanying, Chen, Wenfang, Li, Zhijian, Chen, Wei, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795802/
https://www.ncbi.nlm.nih.gov/pubmed/35165522
http://dx.doi.org/10.7150/ijms.65036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795802/
https://www.ncbi.nlm.nih.gov/pubmed/35165522
http://dx.doi.org/10.7150/ijms.65036

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