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TGR5 Activation Ameliorates Mitochondrial Homeostasis via Regulating the PKCδ/Drp1-HK2 Signaling in Diabetic Retinopathy

Background: Diabetic retinopathy (DR) is one of the most important microvascular diseases of diabetes. Our previous research demonstrated that bile acid G-protein-coupled membrane receptor (TGR5), a novel cell membrane receptor of bile acid, ameliorates the vascular endothelial cell dysfunction in D...

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Detalles Bibliográficos
Autores principales: Zhang, Meng-Yuan, Zhu, Lingpeng, Zheng, Xinhua, Xie, Tian-Hua, Wang, Wenjuan, Zou, Jian, Li, Yan, Li, Hong-Ying, Cai, Jiping, Gu, Shun, Yao, Yong, Wei, Ting-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795816/
https://www.ncbi.nlm.nih.gov/pubmed/35096809
http://dx.doi.org/10.3389/fcell.2021.759421