SARS-CoV-2 variants of concern display enhanced intrinsic pathogenic properties and expanded organ tropism in mouse models

SARS-CoV-2 variants of concern (VOCs) display enhanced transmissibility and resistance to antibody neutralization. Comparing the early 2020 isolate EU-1 to the VOCs Alpha, Beta, and Gamma in mice transgenic for human ACE2 reveals that VOCs induce a broadened scope of symptoms, expand systemic infect...

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Detalles Bibliográficos
Autores principales: Stolp, Bettina, Stern, Marcel, Ambiel, Ina, Hofmann, Katharina, Morath, Katharina, Gallucci, Lara, Cortese, Mirko, Bartenschlager, Ralf, Ruggieri, Alessia, Graw, Frederik, Rudelius, Martina, Keppler, Oliver Till, Fackler, Oliver Till
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795826/
https://www.ncbi.nlm.nih.gov/pubmed/35134331
http://dx.doi.org/10.1016/j.celrep.2022.110387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8795826/
https://www.ncbi.nlm.nih.gov/pubmed/35134331
http://dx.doi.org/10.1016/j.celrep.2022.110387

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