piRNAs initiate transcriptional silencing of spermatogenic genes during C. elegans germline development

Eukaryotic genomes harbor invading transposable elements that are silenced by PIWI-interacting RNAs (piRNAs) to maintain genome integrity in animal germ cells. However, whether piRNAs also regulate endogenous gene expression programs remains unclear. Here, we show that C. elegans piRNAs trigger the...

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Detalles Bibliográficos
Autores principales: Cornes, Eric, Bourdon, Loan, Singh, Meetali, Mueller, Florian, Quarato, Piergiuseppe, Wernersson, Erik, Bienko, Magda, Li, Blaise, Cecere, Germano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796119/
https://www.ncbi.nlm.nih.gov/pubmed/34921763
http://dx.doi.org/10.1016/j.devcel.2021.11.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796119/
https://www.ncbi.nlm.nih.gov/pubmed/34921763
http://dx.doi.org/10.1016/j.devcel.2021.11.025

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