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Synthesis of Azido-Globo H Analogs for Immunogenicity Evaluation

[Image: see text] Globo H (GH) is a tumor-associated carbohydrate antigen (TACA), and GH conjugations have been evaluated as potential cancer vaccines. However, like all carbohydrate-based vaccines, low immunogenicity is a major issue. Modifications of the TACA increase its immunogenicity, but the s...

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Detalles Bibliográficos
Autores principales: Chen, Chiang-Yun, Lin, Yu-Wei, Wang, Szu-Wen, Lin, Yung-Chu, Cheng, Yang-Yu, Ren, Chien-Tai, Wong, Chi-Huey, Wu, Chung-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796297/
https://www.ncbi.nlm.nih.gov/pubmed/35106375
http://dx.doi.org/10.1021/acscentsci.1c01277