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Synthesis of Azido-Globo H Analogs for Immunogenicity Evaluation
[Image: see text] Globo H (GH) is a tumor-associated carbohydrate antigen (TACA), and GH conjugations have been evaluated as potential cancer vaccines. However, like all carbohydrate-based vaccines, low immunogenicity is a major issue. Modifications of the TACA increase its immunogenicity, but the s...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796297/ https://www.ncbi.nlm.nih.gov/pubmed/35106375 http://dx.doi.org/10.1021/acscentsci.1c01277 |