Scalable Subsecond Synthesis of Drug Scaffolds via Aryllithium Intermediates by Numbered-up 3D-Printed Metal Microreactors

[Image: see text] Continuous-flow microreactors enable ultrafast chemistry; however, their small capacity restricts industrial-level productivity of pharmaceutical compounds. In this work, scale-up subsecond synthesis of drug scaffolds was achieved via a 16 numbered-up printed metal microreactor (16...

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Detalles Bibliográficos
Autores principales: Kang, Ji-Ho, Ahn, Gwang-Noh, Lee, Heekwon, Yim, Se-Jun, Lahore, Santosh, Lee, Hyune-Jea, Kim, Heejin, Kim, Ji Tae, Kim, Dong-Pyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796307/
https://www.ncbi.nlm.nih.gov/pubmed/35106371
http://dx.doi.org/10.1021/acscentsci.1c00972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796307/
https://www.ncbi.nlm.nih.gov/pubmed/35106371
http://dx.doi.org/10.1021/acscentsci.1c00972

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