Plasma protein binding prediction focusing on residue-level features and circularity of cyclic peptides by deep learning

MOTIVATION: In recent years, cyclic peptide drugs have been receiving increasing attention because they can target proteins that are difficult to be tackled by conventional small-molecule drugs or antibody drugs. Plasma protein binding rate ([Formula: see text]) is a significant pharmacokinetic prop...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jianan, Yanagisawa, Keisuke, Yoshikawa, Yasushi, Ohue, Masahito, Akiyama, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796384/
https://www.ncbi.nlm.nih.gov/pubmed/34849593
http://dx.doi.org/10.1093/bioinformatics/btab726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796384/
https://www.ncbi.nlm.nih.gov/pubmed/34849593
http://dx.doi.org/10.1093/bioinformatics/btab726

Ejemplares similares