Endoplasmic reticulum stress promotes the release of exosomal PD-L1 from head and neck cancer cells and facilitates M2 macrophage polarization

BACKGROUND: Endoplasmic reticulum (ER) stress has been found to foster the escape of cancer cells from immune surveillance and upregulate PD-L1 expression. However, the underlying mechanisms are unknown. METHODS: While analyzing the protein levels using immunofluorescence and Western blotting, the R...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Yi, Jiao, Pengfei, Wang, Zeyu, Chen, Mengqi, Du, Hongming, Xu, Liang, Xu, Juanyong, Dai, Youjin, Wu, Fu-gen, Zhang, Yaqin, Wu, Heming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796490/
https://www.ncbi.nlm.nih.gov/pubmed/35090495
http://dx.doi.org/10.1186/s12964-021-00810-2

Ejemplares similares

Ejemplares similares