Human in silico trials for parametric computational fluid dynamics investigation of cerebrospinal fluid drug delivery: impact of injection location, injection protocol, and physiology

BACKGROUND: Intrathecal drug delivery has a significant role in pain management and central nervous system (CNS) disease therapeutics. A fluid-physics based tool to assist clinicians in choosing specific drug doses to the spine or brain may help improve treatment schedules. METHODS: This study appli...

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Detalles Bibliográficos
Autores principales: Khani, Mohammadreza, Burla, Goutham Kumar Reddy, Sass, Lucas R., Arters, Ostin N., Xing, Tao, Wu, Haiming, Martin, Bryn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796513/
https://www.ncbi.nlm.nih.gov/pubmed/35090516
http://dx.doi.org/10.1186/s12987-022-00304-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796513/
https://www.ncbi.nlm.nih.gov/pubmed/35090516
http://dx.doi.org/10.1186/s12987-022-00304-4

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