miR-155 inhibits chondrocyte pyroptosis in knee osteoarthritis by targeting SMAD2 and inhibiting the NLRP3/Caspase-1 pathway

OBJECTIVE: Knee osteoarthritis (KOA) is based on degenerative pathological changes. miR-155 is involved in regulating KOA. This study estimated the mechanism of miR-155 in mouse KOA chondrocytes. METHODS: Mouse KOA chondrocyte model was established by lipopolysaccharide (LPS) induction and identifie...

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Detalles Bibliográficos
Autores principales: Li, Gen, Xiu, Lijun, Li, Xiaoyun, Ma, Lisha, Zhou, Jihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796562/
https://www.ncbi.nlm.nih.gov/pubmed/35090521
http://dx.doi.org/10.1186/s13018-021-02886-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796562/
https://www.ncbi.nlm.nih.gov/pubmed/35090521
http://dx.doi.org/10.1186/s13018-021-02886-5

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