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miR-199b-3p contributes to acquired resistance to cetuximab in colorectal cancer by targeting CRIM1 via Wnt/β-catenin signaling

BACKGROUND: Despite advances in the development of efficient chemotherapy, the treatment of colorectal cancer (CRC) remains a challenge due to acquired chemoresistance. It has been reported that microRNAs (miRNAs) dysregulation is associated with the development of chemoresistance. Recently, the exp...

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Detalles Bibliográficos
Autores principales: Han, Hu, Li, Yan, Qin, Wan, Wang, Lu, Yin, Han, Su, Beibei, Yuan, Xianglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796585/
https://www.ncbi.nlm.nih.gov/pubmed/35090460
http://dx.doi.org/10.1186/s12935-022-02460-x