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Wogonin reduces cardiomyocyte apoptosis from mitochondrial release of cytochrome c to improve doxorubicin-induced cardiotoxicity

Doxorubicin (DOX) has powerful anticancer properties, but its clinical application is affected by its serious cardiotoxicity. Wogonin (WG) has been shown to have marked cardiovascular protection potential. However, it is not known whether this potential can protect the heart from DOX damage. The aim...

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Detalles Bibliográficos
Autores principales: Wei, Yunjie, Zhao, Junhao, Xiong, Jian, Chai, Jingjing, Yang, Xi, Wang, Junfeng, Chen, Jiajuan, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8796616/
https://www.ncbi.nlm.nih.gov/pubmed/35126708
http://dx.doi.org/10.3892/etm.2022.11128