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Parallel evolution of a splicing program controlling neuronal excitability in flies and mammals

Alternative splicing increases neuronal transcriptomic complexity throughout animal phylogeny. To delve into the mechanisms controlling the assembly and evolution of this regulatory layer, we characterized the neuronal microexon program in Drosophila and compared it with that of mammals. In nonverte...

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Detalles Bibliográficos
Autores principales: Torres-Méndez, Antonio, Pop, Sinziana, Bonnal, Sophie, Almudi, Isabel, Avola, Alida, Roberts, Ruairí J. V., Paolantoni, Chiara, Alcaina-Caro, Ana, Martín-Anduaga, Ane, Haussmann, Irmgard U., Morin, Violeta, Casares, Fernando, Soller, Matthias, Kadener, Sebastian, Roignant, Jean-Yves, Prieto-Godino, Lucia, Irimia, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797185/
https://www.ncbi.nlm.nih.gov/pubmed/35089784
http://dx.doi.org/10.1126/sciadv.abk0445