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Functional analysis of ADARs in planarians supports a bilaterian ancestral role in suppressing double-stranded RNA-response

ADARs (adenosine deaminases acting on RNA) are known for their adenosine-to-inosine RNA editing activity, and most recently, for their role in preventing aberrant dsRNA-response by activation of dsRNA sensors (i.e., RIG-I-like receptor homologs). However, it is still unclear whether suppressing spur...

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Detalles Bibliográficos
Autor principal: Bar Yaacov, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797187/
https://www.ncbi.nlm.nih.gov/pubmed/35041722
http://dx.doi.org/10.1371/journal.ppat.1010250