Overexpression of chromodomain helicase DNA binding protein 5 (CHD5) inhibits cell proliferation and induces cell cycle arrest and apoptosis in chronic myeloid leukemia

BACKGROUND: Chromodomain helicase DNA binding protein 5 (CHD5) was reported to be a tumor suppressor and our previous work showed CHD5 was epigenetically inactivated in human chronic myeloid leukemia (CML). This study aimed to investigate the effect of its overexpression on CML tumorigenesis. METHOD...

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Detalles Bibliográficos
Autores principales: Xiong, Shilin, Yan, Qitao, Peng, Yiqi, Huang, Sheng, Zhao, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797277/
https://www.ncbi.nlm.nih.gov/pubmed/35116408
http://dx.doi.org/10.21037/tcr-20-2276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797277/
https://www.ncbi.nlm.nih.gov/pubmed/35116408
http://dx.doi.org/10.21037/tcr-20-2276

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