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The hypermethylation of the CDKN2A and CHFR promoter region is a key regulatory mechanism of CDKN2A and CHFR expression in esophageal squamous cell carcinoma

BACKGROUND: The aim of this study was to evaluate the correlation between CDKN2A and CHFR expression and the methylation status of the CpG island in the promoter region of esophageal squamous cell carcinoma (ESCC) cell lines, radioresistant ESCC cell lines and ESCC clinical tissue specimens. METHODS...

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Detalles Bibliográficos
Autores principales: Mei, Xinyu, Cheng, Min, Chen, Wen, Wu, Xianning, Xie, Mingran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797354/
https://www.ncbi.nlm.nih.gov/pubmed/35116815
http://dx.doi.org/10.21037/tcr.2019.04.19