Targeting BRD9 by I-BRD9 efficiently inhibits growth of acute myeloid leukemia cells

BACKGROUND: Acute myeloid leukemia (AML) is characterized by genetic and epigenetic mutations that lead to a block in differentiation as well as unrestrained proliferation. Many epigenetic regulators have been shown to be important for AML initiation and development. Among these, bromodomain-contain...

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Detalles Bibliográficos
Autores principales: Zhou, Lixin, Yao, Qi, Li, Hui, Chen, Jieping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797396/
https://www.ncbi.nlm.nih.gov/pubmed/35116642
http://dx.doi.org/10.21037/tcr-21-42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797396/
https://www.ncbi.nlm.nih.gov/pubmed/35116642
http://dx.doi.org/10.21037/tcr-21-42

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