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Targeting BRD9 by I-BRD9 efficiently inhibits growth of acute myeloid leukemia cells
BACKGROUND: Acute myeloid leukemia (AML) is characterized by genetic and epigenetic mutations that lead to a block in differentiation as well as unrestrained proliferation. Many epigenetic regulators have been shown to be important for AML initiation and development. Among these, bromodomain-contain...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
AME Publishing Company
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797396/ https://www.ncbi.nlm.nih.gov/pubmed/35116642 http://dx.doi.org/10.21037/tcr-21-42 |