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Grape seed proanthocyanidin extract induces apoptosis of HL-60/ADR cells via the Bax/Bcl-2 caspase-3/9 signaling pathway

BACKGROUND: Our previous study detailed the direct induction of apoptosis by grape seed proanthocyanidin extract (GSPE) in a multidrug resistant human acute myeloid leukemia (AML) HL-60/adriamycin (HL-60/ADR) cell line, although the mechanism of this effect was not detailed. This study aims to eluci...

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Detalles Bibliográficos
Autores principales: Lin, Ka-Na, Zhao, Wei, Huang, Shi-Ying, Li, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797540/
https://www.ncbi.nlm.nih.gov/pubmed/35116693
http://dx.doi.org/10.21037/tcr-21-920