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ShRNA-mediated silencing of hTERT promote apoptosis and senescence in human ovarian cancer cells
BACKGROUND: Human telomerase reverse transcriptase (hTERT) is a crucial oncogene and a key factor in cell immortalization. Apart from hematopoiesis stem cell and germ cells, normal cells and tissues almost no expression of this gene. However, the positive expression rate of hTERT in malignant tumors...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797648/ https://www.ncbi.nlm.nih.gov/pubmed/35116789 http://dx.doi.org/10.21037/tcr.2019.03.17 |