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ShRNA-mediated silencing of hTERT promote apoptosis and senescence in human ovarian cancer cells

BACKGROUND: Human telomerase reverse transcriptase (hTERT) is a crucial oncogene and a key factor in cell immortalization. Apart from hematopoiesis stem cell and germ cells, normal cells and tissues almost no expression of this gene. However, the positive expression rate of hTERT in malignant tumors...

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Detalles Bibliográficos
Autores principales:	Su, Chen, Luo, Yi, Yang, Yaying, Yi, Yongfen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797648/ https://www.ncbi.nlm.nih.gov/pubmed/35116789 http://dx.doi.org/10.21037/tcr.2019.03.17

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