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Multi-omics analysis reveals the BRCA1 mutation and mismatch repair gene signatures associated with survival, protein expression, and copy number alterations in prostate cancer

BACKGROUND: Recent genomic analysis reveals that DNA repair gene mutations can be detected in 15–30% of patients in metastatic castration resistant prostate cancer depending on the population and clinical setting when comparing to a very small fraction in those with indolent localized diseases. The...

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Detalles Bibliográficos
Autores principales: Hsiao, Tzu-Hung, Chiu, Yu-Chiao, Shao, Yu-Hsuan Joni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797674/
https://www.ncbi.nlm.nih.gov/pubmed/35116870
http://dx.doi.org/10.21037/tcr.2019.07.05