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Multi-omics analysis reveals the BRCA1 mutation and mismatch repair gene signatures associated with survival, protein expression, and copy number alterations in prostate cancer
BACKGROUND: Recent genomic analysis reveals that DNA repair gene mutations can be detected in 15–30% of patients in metastatic castration resistant prostate cancer depending on the population and clinical setting when comparing to a very small fraction in those with indolent localized diseases. The...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797674/ https://www.ncbi.nlm.nih.gov/pubmed/35116870 http://dx.doi.org/10.21037/tcr.2019.07.05 |