Down-regulation of PSMD4 can attenuate autophagy, enhance the accumulation of intracellular ROS, and increase the sensitivity of epithelial ovarian cancer to carboplatin by inhibiting the NF-κB pathway

BACKGROUND: The incidence of ovarian cancer ranks third among female gynecological cancers in the world, and more than 90% of patients are epithelial ovarian cancer (EOC). Carboplatin is the first-line chemotherapy drug for the treatment of EOC patients. However, patients who are resistant to carbop...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ying, Zhou, Qin, Shen, Jing, Zhu, Lixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797679/
https://www.ncbi.nlm.nih.gov/pubmed/35116329
http://dx.doi.org/10.21037/tcr-21-1389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797679/
https://www.ncbi.nlm.nih.gov/pubmed/35116329
http://dx.doi.org/10.21037/tcr-21-1389

Ejemplares similares