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Claudin 18.2 expression in various tumor types and its role as a potential target in advanced gastric cancer

BACKGROUND: Alterations in claudin expression can impair tight junction function, influence signaling pathways, and act as a tumor-promoting event in some epithelial cancers. Recently, zolbetuximab, a highly potent and tumor cell-selective therapeutic antibody against claudin 18.2, has been develope...

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Detalles Bibliográficos
Autores principales: Hong, Jung Yong, An, Ji Yeong, Lee, Jeeyun, Park, Se Hoon, Park, Joon Oh, Park, Young Suk, Lim, Ho Yeong, Kim, Kyoung-Mee, Kang, Won Ki, Kim, Seung Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797704/
https://www.ncbi.nlm.nih.gov/pubmed/35117702
http://dx.doi.org/10.21037/tcr-19-1876