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Claudin 18.2 expression in various tumor types and its role as a potential target in advanced gastric cancer
BACKGROUND: Alterations in claudin expression can impair tight junction function, influence signaling pathways, and act as a tumor-promoting event in some epithelial cancers. Recently, zolbetuximab, a highly potent and tumor cell-selective therapeutic antibody against claudin 18.2, has been develope...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797704/ https://www.ncbi.nlm.nih.gov/pubmed/35117702 http://dx.doi.org/10.21037/tcr-19-1876 |