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Human cancer cells compensate the genes unfavorable for translation by N(6)-methyladenosine modification and enhance their translation efficiency
BACKGROUND: N(6)-methyladenosine (m(6)A) is the methylation of RNA adenosines that participates in multiple biological processes, such as facilitating translation of host genes via the reader protein YTHDF1. The core writer protein of m(6)A in humans is METTL3. METHODS: We utilized YTHDF1 target gen...
Autores principales: | Chu, Duan, Wei, Lai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797713/ https://www.ncbi.nlm.nih.gov/pubmed/35116782 http://dx.doi.org/10.21037/tcr.2019.03.04 |
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