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Chronic nicotine exposure affects programmed death-ligand 1 expression and sensitivity to epidermal growth factor receptor-tyrosine kinase inhibitor in lung cancer

BACKGROUND: Smoking histories are independently associated with poor response to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC) patients with activating EGFR mutations. The aim of the present study was to determine the effect of nicoti...

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Detalles Bibliográficos
Autores principales: Yeo, Chang Dong, Kim, In Kyoung, Ban, Woo Ho, Kang, Hye Seon, Kim, Jin Woo, Kim, Seung Joon, Park, Jong Y., Lee, Sang Haak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797781/
https://www.ncbi.nlm.nih.gov/pubmed/35117115
http://dx.doi.org/10.21037/tcr.2019.05.02