IL-35 inhibits CD8(+) T cells activity by suppressing expression of costimulatory molecule CD28 and Th1 cytokine production

BACKGROUND: Interleukin-35 (IL-35), a novel immune-suppressing cytokine, can promote tumor angiogenesis and inhibits anti-tumor cytotoxic lymphocyte response. Here, we aimed to investigate the potential mechanism of the effects of IL-35 on anti-tumor cytotoxic lymphocyte. METHODS: Dendritic cells (D...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Hua, Zhang, Ting, Yan, Mao-Xiao, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797787/
https://www.ncbi.nlm.nih.gov/pubmed/35116874
http://dx.doi.org/10.21037/tcr.2019.07.30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797787/
https://www.ncbi.nlm.nih.gov/pubmed/35116874
http://dx.doi.org/10.21037/tcr.2019.07.30

Ejemplares similares