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IL-35 inhibits CD8(+) T cells activity by suppressing expression of costimulatory molecule CD28 and Th1 cytokine production

BACKGROUND: Interleukin-35 (IL-35), a novel immune-suppressing cytokine, can promote tumor angiogenesis and inhibits anti-tumor cytotoxic lymphocyte response. Here, we aimed to investigate the potential mechanism of the effects of IL-35 on anti-tumor cytotoxic lymphocyte. METHODS: Dendritic cells (D...

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Detalles Bibliográficos
Autores principales:	Jiang, Hua, Zhang, Ting, Yan, Mao-Xiao, Wu, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797787/ https://www.ncbi.nlm.nih.gov/pubmed/35116874 http://dx.doi.org/10.21037/tcr.2019.07.30

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