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Involvement of DNA methyltransferase 1 (DNMT1) and multidrug resistance-associated proteins in 2-methoxyestradiol-induced cytotoxicity in EC109/Taxol cells

BACKGROUND: Due to acquired drug resistance, paclitaxel-based chemotherapy has limited clinical effects in the treatment of various tumors including esophageal cancer. This study analyzes the hypothesis that paclitaxel resistance is related to changes in the expression of DNA methyltransferase 1 (DN...

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Detalles Bibliográficos
Autores principales: Yang, Qingqing, Guo, Xiaojing, Xu, Yue, Duan, Chang, Wang, Haofan, Feng, Quanling, Zhang, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797790/
https://www.ncbi.nlm.nih.gov/pubmed/35116235
http://dx.doi.org/10.21037/tcr-20-2678