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Fumarate hydratase deficiency induces chronic myeloid leukemia progression

BACKGROUND: Although tyrosine kinase inhibitors (TKIs) have profoundly improved the prognosis of chronic myeloid leukemia (CML), the mechanism of the progression to blast phase (BP) is currently unclear. Our previous study indicated that CML-BP cells utilize glycolysis to proliferate and that the fu...

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Detalles Bibliográficos
Autores principales: Li, Shan, Qiao, Chun, Yang, Lijia, Hong, Ming, Fang, Yu, Jin, Hui, Li, Jianyong, Qian, Sixuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797861/
https://www.ncbi.nlm.nih.gov/pubmed/35116792
http://dx.doi.org/10.21037/tcr.2019.03.23