Cargando…

The E3 protein ubiquitin ligase Itch is a potential target in myeloid malignancies with marrow fibrosis

BACKGROUND: The underlying mechanism of myeloid malignancies like myelodysplastic syndrome (MDS) and acute myelocytic leukemia (AML) with bone marrow (BM) fibrosis (hereafter referred to as MDS-F and AML-F) is not fully understood. This study aimed to investigate the role of the E3 protein ubiquitin...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Shuang, Zhang, Yao, Guo, Cha, Chang, Chunkang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797868/
https://www.ncbi.nlm.nih.gov/pubmed/35116552
http://dx.doi.org/10.21037/tcr-20-3115