Promotion of Ros-mediated Bax/Cyt-c apoptosis by polyphyllin II leads to suppress growth and aggression of glioma cells

BACKGROUND: Gliomas remain among the most difficult cancers to treat, with a 5-year overall survival no greater than 5%. Many saponins showed a wide spectrum of anti-cancer activities at low concentration. Polyphyllin II is one of the common saponins from Paris polyphylla. However, the effect of Pol...

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Detalles Bibliográficos
Autores principales: Cheng, Guang, Xue, Yu-Ye, Fang, Fei, Sun, Guang-Qiang, Lu, Yun-Yang, Ji, Yu-Qiang, Qiu, Peng-Cheng, Tang, Hai-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797898/
https://www.ncbi.nlm.nih.gov/pubmed/35116689
http://dx.doi.org/10.21037/tcr-21-966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8797898/
https://www.ncbi.nlm.nih.gov/pubmed/35116689
http://dx.doi.org/10.21037/tcr-21-966

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